Nosocomial Candida - Epidemiology, transmission, and prevention

The microbiologic profile of organisms causing nosocomial infections has changed significantly in the last decade. Numerous factors, including wider availability of broad-spectrum antibiotics, increased use of invasive indwelling devices, advances in transplantation techniques, and immunosuppressive conditions, account for the emergence of Candida species as prominent etiologic agents of nosocomial bloodstream infections. Cost containment pressures demand improved efficiency in diagnosing and treating candidal infections. Newer antifungal agents must be provided to help contain an emerging group of nosocomial pathogens.