Advances in Y chromosome mapping

被引:9
作者
Yen, PH [1 ]
机构
[1] Univ Calif Los Angeles, Harbor Med Ctr, Div Med Genet, Torrance, CA 90502 USA
关键词
D O I
10.1097/00001703-199906000-00008
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
The human Y chromosome has long been recognized as being responsible for sex determination. In fact, it also encodes more than 30 genes and gene families that participate in a variety of cellular functions, including bone development, tooth growth, and spermatogenesis. De-novo deletion of Y chromosome segments that contain spermatogenesis genes occurs frequently, resulting in low sperm production and male infertility. This article reviews our current knowledge of the structure and function of the Y chromosome is reviewed. (C) 1999 Lippincott Williams & Wilkins.
引用
收藏
页码:275 / 281
页数:7
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