Effect on Blood Loss and Cost-Effectiveness of Pain Cocktails, Platelet-Rich Plasma, or Fibrin Sealant After Total Knee Arthroplasty

被引：17

作者：

Bernasek, Thomas L. ^{[1
]}

Burris, R. Brandon ^{[2
]}

Fujii, Hideki ^{[3
]}

Levering, Melissa F. ^{[3
]}

Polikandriotis, John A. ^{[3
]}

Patterson, Jared J. ^{[1
]}

机构：

[1] Florida Orthopaed Inst, Tampa, FL 33637 USA

[2] Univ S Florida, Dept Orthopaed & Sports Med, Tampa, FL USA

[3] Fdn Orthopaed Res & Educ, Tampa, FL USA

来源：

JOURNAL OF ARTHROPLASTY | 2012年 / 27卷 / 08期

关键词：

total knee arthroplasty; platelet-rich plasma; fibrin sealant; pain cocktail; RANDOMIZED CONTROLLED-TRIAL; TRANEXAMIC ACID; TRANSFUSION; REPLACEMENT; GEL; HEMOGLOBIN; TISSUE;

D O I：

10.1016/j.arth.2012.02.018

中图分类号：

R826.8 [整形外科学]; R782.2 [口腔颌面部整形外科学]; R726.2 [小儿整形外科学]; R62 [整形外科学（修复外科学）];

学科分类号：

摘要：

This study evaluated the effect of periarticular pain cocktail, platelet-rich plasma, or fibrin sealant injections on blood loss, transfusion rate, and hospital costs after total knee arthroplasty. A retrospective review of 400 patients undergoing primary total knee arthroplasty with one of the different periarticular treatments as stated above was performed. Postoperative blood loss, hemoglobin levels, allogenic blood transfusion rates, and per-case hospital injection cost were reported. Although platelet-rich plasma and fibrin sealant decreased blood loss compared with the control group (P < .001), there was no significant difference in blood loss in the paincocktail group or in postoperative hemoglobin levels or transfusion rates between all groups. Significant efficacy arid cost-effectiveness for these modalities could not be identified and have, therefore, been discontinued at our practice.

引用

页码：1448 / 1451

页数：4

共 14 条

[1]

Anderson Lucas A, 2009, J Knee Surg, V22, P130

[2] Risks associated with blood transfusion after total knee arthroplasty [J].