Dialysis time, survival, and dose-targeting bias

被引:20
作者
Daugirdas, John T. [1 ]
机构
[1] Univ Illinois, Coll Med, Dept Med, Div Nephrol, Chicago, IL 60612 USA
关键词
HEMODIALYSIS; MORTALITY; MORBIDITY; LENGTH;
D O I
10.1038/ki.2012.365
中图分类号
R5 [内科学]; R69 [泌尿科学(泌尿生殖系疾病)];
学科分类号
100201 [内科学]; 100221 [泌尿外科学];
摘要
Dialysis time is increasingly being appreciated as an important measure of dialysis adequacy. Increased dialysis time leads to better control of volume excess, to reduced occurrence of intradialytic hypotension, and to better control of serum phosphorus. Nevertheless, the amount of benefit obtainable by moderate increases in dialysis time in patients following a three-times-per-week schedule has not been well established, and the analysis is confounded by associations between prescribed and/or delivered dialysis time and factors related to patient mortality. Kidney International (2012) 83, 9-13. doi:10.1038/ki.2012.365
引用
收藏
页码:9 / 13
页数:5
相关论文
共 15 条
[1]
Shorter dialysis times are associated with higher mortality among incident hemodialysis patients [J].
Brunelli, Steven M. ;
Chertow, Glenn M. ;
Ankers, Elizabeth D. ;
Lowrie, Edmund G. ;
Thadhani, Ravi .
KIDNEY INTERNATIONAL, 2010, 77 (07) :630-636
[2]
Hemodialysis-Induced Cardiac Injury: Determinants and Associated Outcomes [J].
Burton, James O. ;
Jefferies, Helen J. ;
Selby, Nicholas M. ;
McIntyre, Christopher W. .
CLINICAL JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, 2009, 4 (05) :914-920
[3]
Importance of normohydration for the long-term survival of haemodialysis patients [J].
Chazot, Charles ;
Wabel, Peter ;
Chamney, Paul ;
Moissl, Ulrich ;
Wieskotten, Sebastian ;
Wizemann, Volker .
NEPHROLOGY DIALYSIS TRANSPLANTATION, 2012, 27 (06) :2404-2410
[4]
Modeled Urea Distribution Volume and Mortality in the HEMO Study [J].
Daugirdas, John T. ;
Greene, Tom ;
Depner, Thomas A. ;
Levin, Nathan W. ;
Chertow, Glenn M. .
CLINICAL JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, 2011, 6 (05) :1129-1138
[5]
Effect of dialysis dose and membrane flux in maintenance hemodialysis. [J].
Eknoyan, G ;
Beck, GJ ;
Cheung, AK ;
Daugirdas, JT ;
Greene, T ;
Kusek, JW ;
Allon, M ;
Bailey, J ;
Delmez, JA ;
Depner, TA ;
Dwyer, JT ;
Levey, AS ;
Levin, NW ;
Milford, E ;
Ornt, DB ;
Rocco, MV ;
Schulman, G ;
Schwab, SJ ;
Teehan, BP ;
Toto, R .
NEW ENGLAND JOURNAL OF MEDICINE, 2002, 347 (25) :2010-2019
[6]
Shorter length dialysis sessions are associated with increased mortality, independent of body weight [J].
Flythe, Jennifer E. ;
Curhan, Gary C. ;
Brunelli, Steven M. .
KIDNEY INTERNATIONAL, 2013, 83 (01) :104-113
[7]
Rapid fluid removal during dialysis is associated with cardiovascular morbidity and mortality [J].
Flythe, Jennifer E. ;
Kimmel, Stephen E. ;
Brunelli, Steven M. .
KIDNEY INTERNATIONAL, 2011, 79 (02) :250-257
[8]
Very Low and High Predialysis Serum Bicarbonate Levels are Risk Factors for Mortality: What are the Appropriate Interventions? [J].
Gennari, F. John .
SEMINARS IN DIALYSIS, 2010, 23 (03) :253-257
[9]
Association of achieved dialysis dose with mortality in the Hemodialysis Study: An example of "dose-targeting bias" [J].
Greene, T ;
Daugirdas, J ;
Depner, T ;
Allon, M ;
Beck, G ;
Chumlea, C ;
Delmez, J ;
Gotch, F ;
Kusek, JW ;
Levin, N ;
Owen, W ;
Schulman, G ;
Star, R ;
Toto, R ;
Eknoyan, G .
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, 2005, 16 (11) :3371-3380
[10]
EFFECT OF THE HEMODIALYSIS PRESCRIPTION ON PATIENT MORBIDITY - REPORT FROM THE NATIONAL COOPERATIVE DIALYSIS STUDY [J].
LOWRIE, EG ;
LAIRD, NM ;
PARKER, TF ;
SARGENT, JA .
NEW ENGLAND JOURNAL OF MEDICINE, 1981, 305 (20) :1176-1181