Signal transduction - Rhapsody in G proteins

被引:13
作者
Bos, JL [1 ]
Zwartkruis, FJT [1 ]
机构
[1] Univ Utrecht, Physiol Chem Lab, NL-3584 CG Utrecht, Netherlands
关键词
D O I
10.1038/23594
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
Guanine-nucleotide-binding proteins are molecular switches that transduce the signals received at a cell's surface to elicit a biological response from the proteins inside. There are two types of G protein — the heterotrimeric G proteins and the small GTPases. New research shows that a well-known small GTPase called Rap1 is regulated by a heterotrimeric G protein, via a GTPase-activating protein called Rap1GAPII.
引用
收藏
页码:820 / 821
页数:2
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