A zebrafish homolog of the serum response factor gene is highly expressed in differentiating embryonic myocytes

被引：10

作者：

Vogel, AM ^{[1
]}

Gerster, T ^{[1
]}

机构：

[1] Univ Basel, Biozentrum, Abt Zellbiol, CH-4056 Basel, Switzerland

来源：

MECHANISMS OF DEVELOPMENT | 1999年 / 81卷 / 1-2期

关键词：

serum response factor; zebrafish; myoD; mef2; muscle; myogenesis;

D O I：

10.1016/S0925-4773(98)00245-7

中图分类号：

Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Serum response factor (SRF) was identified as an activity binding upon serum stimulation of HeLa cells to a motif known as the serum response element in the c-fos promoter. This element is also found in the regulatory regions of many muscle-specific genes. We have characterized srf expression during early zebrafish embryogenesis. In addition to low-level expression in many or even all cells, elevated levels of srf RNA and protein are transiently expressed in skeletal muscle lineages during their differentiation. (C) 1999 Elsevier Science Ireland Ltd. All rights reserved.

引用

页码：217 / 221

页数：5

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