Synthesis and Characterization of Biocompatible Poly(ethylene glycol)-b-Poly(L-lactide) and Study on Their Electrospun Scaffolds

被引：31

作者：

Jiang, Shengbin ^{[1
,2
]}

Liao, Guiying ^{[1
]}

机构：

[1] China Univ Geosci, Fac Mat Sci & Chem Engn, Wuhan 430074, Peoples R China

[2] Hubei Res Inst Chem, Wuhan, Peoples R China

来源：

POLYMER-PLASTICS TECHNOLOGY AND ENGINEERING | 2012年 / 51卷 / 12期

基金：

美国国家科学基金会;

关键词：

Electrospinning; Fiber; Poly(ethylene glycol); Poly(L-lactide); MECHANICAL-PROPERTIES; L-LACTIDE; GLYCOL); PLA; NANOFIBERS; COPOLYMERS; MEMBRANE; DELIVERY;

D O I：

10.1080/03602559.2012.698686

中图分类号：

O63 [高分子化学（高聚物）];

学科分类号：

070305 [高分子化学与物理];

摘要：

A series of multiblock copolymer, Poly(L-lactide)-b-Poly (ethylene glycol) (PLLA-b-PEG) were synthesized and characterized by Fourier transform infrared spectra, differential scanning calorimetry and wide angle X-ray diffraction. PLLA-b-PEG fibrous scaffolds were prepared by electrospinning. The morphology of the fibers was affected by the solution concentration and different weight ratio of PLLA/PEG. In comparison with the electrospun PLLA membrane, the electrospun fibrous membranes of PLLA-b-PEG demonstrated an enhanced water absorption percentage and reductive water contact angle. The electrospun PLLA-b-PEG with weight ratio 90/10 and 75/25 fibrous membranes exhibited good flexibility and deformability to be beneficial for tissue engineering scaffolds.

引用

页码：1237 / 1244

页数：8

共 41 条

[1]

Synthesis and Substrate-Aided Alignment of Porphyrinated Poly(ethylene oxide) (PEO) Electrospun Nanofibers [J].