Molecular control of nitric oxide synthases in the cardiovascular system

被引：147

作者：

Papapetropoulos, A ^{[1
]}

Rudic, RD ^{[1
]}

Sessa, WC ^{[1
]}

机构：

[1] Yale Univ, Sch Med, Boyer Ctr Mol Med, Dept Pharmacol,Mol Cardiobiol Program, New Haven, CT 06536 USA

来源：

CARDIOVASCULAR RESEARCH | 1999年 / 43卷 / 03期

关键词：

nitric oxide synthases; molecular control; cardiovascular system;

D O I：

10.1016/S0008-6363(99)00161-3

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Nitric oxide plays an important role in cardiovascular homeostasis. In this review, the regulation of the three nitric oxide synthase isoforms in the cardiovascular system are examined at molecular and cellular levels. In addition, recent information gleaned from the use of NOS knockout mice are discussed. (C) 1999 Elsevier Science B.V. All rights reserved.

引用

收藏

页码：509 / 520

页数：12

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