Is there any possibility of fertility-sparing surgery in patients with clear-cell carcinoma of the ovary?

被引：29

作者：

Kajiyama, Hiroaki ^{[1
]}

Shibata, Kiyosumi ^{[1
]}

Suzuki, Shiro ^{[1
]}

Ino, Kazuhiko ^{[1
]}

Yamamoto, Eiko ^{[1
]}

Mizuno, Kimio ^{[2
]}

Sakakibara, Katsumi ^{[3
]}

Matsuzawa, Katsuji

Takeda, Akihiro ^{[4
]}

Kinoshita, Yoshito

Kawai, Michiyasu ^{[5
]}

Nagasaka, Tetsuro ^{[6
]}

Nawa, Akihiro ^{[1
]}

Kikkawa, Fumitaka ^{[1
]}

机构：

[1] Nagoya Univ, Dept Obstet & Gynecol, Grad Sch Med, Showa Ku, Nagoya, Aichi 4668550, Japan

[2] Japanese Red Cross Nagoya First Hosp, Dept Obstet & Gynecol, Nagoya, Aichi, Japan

[3] Okazaki Municipal Hosp, Dept Obstet & Gynecol, Okazaki, Aichi, Japan

[4] Gifu Prefectural Tajimi Hosp, Dept Obstet & Gynecol, Gifu, Japan

[5] Toyohashi Muncipal Hosp, Dept Obstet & Gynecol, Toyohashi, Aichi, Japan

[6] Nagoya Univ Hosp, Div Pathol, Clin Lab, Nagoya, Aichi, Japan

来源：

GYNECOLOGIC ONCOLOGY | 2008年 / 111卷 / 03期

关键词：

Clear-cell carcinoma of the ovary (CCC); Fertility-sparing surgery; Pregnancy; Clinical outcome;

D O I：

10.1016/j.ygyno.2008.04.001

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 [肿瘤学];

摘要：

Background. In epithelial ovarian cancer (EOC), fertility-sparing surgery (FSS) has mainly been chosen for stage IA disease. The purpose of this Study was to clarify the clinical Outcome of patients with clear-cell carcinoma of the ovary (CCC) who would usually undergo radical surgery. Cases. After a central pathological review and search of the medical records from multiple institutions between 1988 and 2005, a total of 10 CCC patients treated with FSS were retrospectively evaluated in the current study. The mean age was 35.9 years (range: 32-39 years). The median follow-up time was 35.4 months (range: 21.7-153.2 months). The stage was IA in 4 patients, and IC in 6 patients {IC(b) in 5 patients, and IC(2) in ones}. Nine patients received adjuvant chemotherapy. Nine patients were alive and one patient with stage IC(2) died of the disease at a follow-up time of 36.8 months. Five pregnancies were observed in 4 patients. Conclusions. Although there is no worldwide criterion for FSS in CCC patients at present, it seems that, in selected patients, this Surgical approach could be adopted. This should be investigated by additional studies in a larger series. (C) 2008 Elsevier Inc. All rights reserved.

引用

页码：523 / 526

页数：4

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