Myosin steps backwards

被引：10

作者：

Schliwa, M ^{[1
]}

机构：

[1] Univ Munich, Adolf Butenandt Inst, D-80336 Munich, Germany

来源：

NATURE | 1999年 / 401卷 / 6752期

关键词：

D O I：

10.1038/46692

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

All myosin motors move in the same direction — or so it was thought. The discovery of one form that acts in reverse sheds new light on the mechanics of these molecular motors.

引用

页码：431 / 432

页数：2

共 15 条

[1] Fifty ways to love your lever: Myosin motors [J].

Block, SM .

CELL, 1996, 87 (02) :151-157

[2]

BLOOM GS, 1995, PROTEIN PROFILE, V2, P1109

[3] The directional preference of kinesin motors is specified by an element outside of the motor catalytic domain [J].

Case, RB ;

Pierce, DW ;

HomBooher, N ;

Hart, CL ;

Vale, RD .

CELL, 1997, 90 (05) :959-966

[4] Crystal structure of a vertebrate smooth muscle myosin motor domain and its complex with the essential light chain: Visualization of the pre-power stroke state [J].

Dominguez, R ;

Freyzon, Y ;

Trybus, KM ;

Cohen, C .

CELL, 1998, 94 (05) :559-571

[5] Determinants of kinesin motor polarity [J].

Endow, SA ;

Waligora, KW .

SCIENCE, 1998, 281 (5380) :1200-1202

[6] Reversal in the direction of movement of a molecular motor [J].

Henningsen, U ;

Schliwa, M .

NATURE, 1997, 389 (6646) :93-96

[7] Atomic structure of scallop myosin subfragment S1 complexed with MgADP:: A novel conformation of the myosin head [J].

Houdusse, A ;

Kalbokis, VN ;

Himmel, D ;

Szent-Györgyi, AG ;

Cohen, C .

CELL, 1999, 97 (04) :459-470

[8] Crystal structure of the kinesin motor domain reveals a structural similarity to myosin [J].

Kull, FJ ;

Sablin, EP ;

Lau, R ;

Fletterick, RJ ;

Vale, RD .

NATURE, 1996, 380 (6574) :550-555

[9] TRANSPORT OF CYTOPLASMIC PARTICLES CATALYZED BY AN UNCONVENTIONAL MYOSIN IN LIVING DROSOPHILA EMBRYOS [J].

MERMALL, V ;

MCNALLY, JG ;

MILLER, KG .

NATURE, 1994, 369 (6481) :560-562

[10] 3-DIMENSIONAL STRUCTURE OF MYOSIN SUBFRAGMENT-1 - A MOLECULAR MOTOR [J].

RAYMENT, I ;

RYPNIEWSKI, WR ;

SCHMIDTBASE, K ;

SMITH, R ;

TOMCHICK, DR ;

BENNING, MM ;

WINKELMANN, DA ;

WESENBERG, G ;

HOLDEN, HM .

SCIENCE, 1993, 261 (5117) :50-58

← 1 2 →