Electrical measurement of adhesion and viability of living cells with a silicon chip

被引:1
作者
Bandiera, L. [1 ]
Borgo, M. [1 ]
Cellere, G. [2 ]
De Toni, A. [2 ]
Santoni, L. [1 ]
Dal Maschio, M. [3 ]
Girardi, S. [3 ]
Lorenzelli, L. [4 ]
Paccagnella, A. [2 ]
机构
[1] Biosilab Srl, I-38068 Rovereto, TN, Italy
[2] Univ Padua, Dept Ingn Informaz, Padua 35131, Italy
[3] Univ Padua, Dept Anatomia Fisiologia Umana, Padua 35131, Italy
[4] FBK, Trento, Italy
来源
2007 IEEE INTERNATIONAL ELECTRON DEVICES MEETING, VOLS 1 AND 2 | 2007年
关键词
D O I
10.1109/IEDM.2007.4419083
中图分类号
T [工业技术];
学科分类号
08 ;
摘要
Silicon biochips are used to study, stimulate and manipulate single (mammalian) cells, whose viability and adhesion are usually studied via subjective, non quantitative, microscope observations. In this work an accurate equivalent model of the biochip/cell system has been developed and successfully applied to experiments, which have permitted to quantitatively correlate cell health status and changes in its membrane morphology to the measured impedance of such system.
引用
收藏
页码:855 / +
页数:2
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