Antidiabetic activity of leaf and callus extracts of Aegle marmelos in rabbit

被引:43
作者
Arumugam, Sevugan [2 ]
Kavimani, Subramanian [3 ]
Kadalmani, Balamuthu [4 ]
Ahmed, Abdul Bakrudeen Ali [1 ]
Akbarsha, Mohammed Abdulkadar [4 ]
Rao, Mandali Venkateswara [1 ]
机构
[1] Bharathidasan Univ, Sch Life Sci, Dept Plant Sci, Tiruchirappalli 620024, India
[2] Natl Taiwan Univ, Taipei 106, Taiwan
[3] Mother Theresa Inst Hlth Sci, Pondicherry, India
[4] Bharathidasan Univ, Sch Life Sci, Dept Anim Sci, Tiruchirappalli 620024, India
来源
SCIENCEASIA | 2008年 / 34卷 / 03期
关键词
Aegle marmelos; callus culture; methanolic extraction; anti-diabetic activity;
D O I
10.2306/scienceasia1513-1874.2008.34.317
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 [理学]; 0710 [生物学]; 09 [农学];
摘要
Aegle marmelos (the bael tree) is a popular medicinal plant in the Ayurveda and Siddha systems of medicine and folk medicines used to treat diabetes. The present study was undertaken to find the extent to which calluses obtained from leaf explant of A. marmelos has a potential for application in diabetes management compared to the ordinary plant material. Treatment using extracts from both leaf and callus produced significant decreases in blood sugar level in streptozotozin diabetic rabbits. Among the various extracts, the methanol extracts of the leaf and callus brought about the maximum anti-diabetic effect. The study revealed that the in vitro callus culture of A. marmelos has as much potential in diabetes management as the original leaf extract.
引用
收藏
页码:317 / 321
页数:5
相关论文
共 23 条
[1]
Anturlikar S. D., 1995, Indian Journal of Physiology and Pharmacology, V39, P95
[2]
Arumugam S, 2003, FOR SCI, V75, P269
[3]
Das Ani V., 1996, Indian Journal of Experimental Biology, V34, P341
[4]
Relative importance of transport and alkylation for pancreatic beta-cell toxicity of streptozotocin [J].
Elsner, M ;
Guldbakke, B ;
Tiedge, M ;
Munday, R ;
Lenzen, S .
DIABETOLOGIA, 2000, 43 (12) :1528-1533
[5]
NUTRIENT REQUIREMENTS OF SUSPENSION CULTURES OF SOYBEAN ROOT CELLS [J].
GAMBORG, OL ;
MILLER, RA ;
OJIMA, K .
EXPERIMENTAL CELL RESEARCH, 1968, 50 (01) :151-+
[6]
Goel R. K., 1997, Indian Journal of Experimental Biology, V35, P1080
[7]
HOOKER JD, 1975, FLORA BRIT INDIA, V1, P516
[8]
ISLAM R, 1995, CURR SCI INDIA, V69, P494
[9]
STUDIES ON CARDIO-ACTIVE CRUDE DRUGS .3. EFFECTS OF CONSTITUENTS OF BELI (AEGLE-MARMELOS) ON SPONTANEOUS BEATING AND CALCIUM-PARADOX OF MYOCARDIAL-CELLS [J].
KAKIUCHI, N ;
SENARATNE, LRE ;
HUANG, SL ;
YANG, XW ;
HATTORI, M ;
PILAPITIYA, U ;
NAMBA, T .
PLANTA MEDICA, 1991, 57 (01) :43-46
[10]
Kamalakkanan N., 2003, Journal of Medicinal Food, V6, P93