Improving dietary patterns in patients with nonalcoholic fatty liver disease

被引:40
作者
Carvalhana, Sofia [1 ]
Machado, Mariana Verdelho [1 ]
Cortez-Pinto, Helena [1 ]
机构
[1] Hosp Santa Maria, Serv Gastroenterol, Fac Med Lisboa, Dept Gastrenterol,Unidade Nutr & Metab,Inst Med M, P-1649035 Lisbon, Portugal
关键词
diet; hepatic steatosis; nonalcoholic fatty liver disease; nonalcoholic steatohepatitis; weight loss; SERUM ALANINE AMINOTRANSFERASE; TEA EXTRACT PROTECTS; TERM HIGH-FAT; GREEN TEA; ALCOHOL-CONSUMPTION; INSULIN-RESISTANCE; HEPATIC STEATOSIS; OXIDATIVE STRESS; FREE-CHOLESTEROL; SATURATED FAT;
D O I
10.1097/MCO.0b013e3283566614
中图分类号
R5 [内科学];
学科分类号
100201 [内科学];
摘要
Purpose of review Nonalcoholic fatty liver disease (NAFLD) is the liver epidemic of our time. Diet strongly influences its development and should be a component of any treatment plan. It is crucial to standardize diet recommendations in an evidence-based manner. Recent findings Calorie restriction per se seems beneficial regardless of macronutrients composition. However, fat consumption, mainly cholesterol and saturated fatty acids are particularly steatogenic. There is increasing evidence that fructose, mainly consumed as soft drinks, is highly deleterious to the liver. Controversial results regarding modest alcohol consumption, suggest that although alcohol should not be advised, it should not be strictly forbidden. Recent studies suggest beneficial effects of coffee and tea in NAFLD. Summary Patients with NAFLD should have an individualized diet recommendation, in order to lose at least 7% of their weight if overweight, reducing caloric intake, mainly at cost of cholesterol and saturated fatty acids. Simple sugars should be avoided, and soft drinks discouraged.
引用
收藏
页码:468 / 473
页数:6
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