Molecular determinants of exocytosis

被引:57
作者
Dieter, B [1 ]
Jahn, R [1 ]
机构
[1] Max Planck Inst Biophys Chem, Dept Neurobiol, D-37077 Gottingen, Germany
来源
PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY | 2002年 / 443卷 / 03期
关键词
exocytosis; membrane fusion; SNARE proteins;
D O I
10.1007/s00424-001-0742-4
中图分类号
Q4 [生理学];
学科分类号
071003 ;
摘要
Membrane fusion processes occur throughout the cell. Among those, exocytosis of secretory organelles is probably one of the fastest fusion events animal cells can achieve. Structural and functional studies have provided a conceptual framework and a starting point for our mechanistic understanding of how SNARE proteins may contribute to the final step in exocytosis.
引用
收藏
页码:333 / 338
页数:6
相关论文
共 60 条
[1]   Stepping rotation of F1-ATPase visualized through angle-resolved single-fluorophore imaging [J].
Adachi, K ;
Yasuda, R ;
Noji, H ;
Itoh, H ;
Harada, Y ;
Yoshida, M ;
Kinosita, K .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2000, 97 (13) :7243-7247
[2]   TRANSMITTER RELEASE FROM SYNAPSES - DOES A PREASSEMBLED FUSION PORE INITIATE EXOCYTOSIS [J].
ALMERS, W ;
TSE, FW .
NEURON, 1990, 4 (06) :813-818
[3]   Fusion needs more than SNAREs [J].
Almers, W .
NATURE, 2001, 409 (6820) :567-568
[4]   Calmodulin is the divalent cation receptor for rapid endocytosis, but not exocytosis, in adrenal chromaffin cells [J].
Artalejo, CR ;
Elhamdani, A ;
Palfrey, HC .
NEURON, 1996, 16 (01) :195-205
[5]   A 15 KDA PROTEOLIPID FOUND IN MEDIATOPHORE PREPARATIONS FROM TORPEDO ELECTRIC ORGAN PRESENTS HIGH SEQUENCE HOMOLOGY WITH THE BOVINE CHROMAFFIN GRANULE PROTONOPHORE [J].
BIRMAN, S ;
MEUNIER, FM ;
LESBATS, B ;
LECAER, JP ;
ROSSIER, J ;
ISRAEL, M .
FEBS LETTERS, 1990, 261 (02) :303-306
[6]  
BIRMAN S, 1987, J NEUROCHEM, V49, P975
[7]   BOTULINUM NEUROTOXIN-A SELECTIVELY CLEAVES THE SYNAPTIC PROTEIN SNAP-25 [J].
BLASI, J ;
CHAPMAN, ER ;
LINK, E ;
BINZ, T ;
YAMASAKI, S ;
DECAMILLI, P ;
SUDHOF, TC ;
NIEMANN, H ;
JAHN, R .
NATURE, 1993, 365 (6442) :160-163
[8]   SYNTAXIN AND SYNAPTOBREVIN FUNCTION DOWNSTREAM OF VESICLE DOCKING IN DROSOPHILA [J].
BROADIE, K ;
PROKOP, A ;
BELLEN, HJ ;
OKANE, CJ ;
SCHULZE, KL ;
SWEENEY, ST .
NEURON, 1995, 15 (03) :663-673
[9]  
Bruns D, 1997, J NEUROSCI, V17, P1898
[10]   Snare-mediated membrane fusion [J].
Chen, YA ;
Scheller, RH .
NATURE REVIEWS MOLECULAR CELL BIOLOGY, 2001, 2 (02) :98-106