Melanoma, Version 2.2013 Featured Updates to the NCCN Guidelines

被引：120

作者：

Coit, Daniel G. ^{[1
]}

Andtbacka, Robert ^{[2
]}

Anker, Christopher J. ^{[2
]}

Bichakjian, Christopher K. ^{[3
]}

Carson, William E., III ^{[4
,5
]}

Daud, Adil ^{[6
]}

DiMaio, Dominick ^{[7
]}

Fleming, Martin D. ^{[8
]}

Guilds, Valerie ^{[9
]}

Halpern, Allan C. ^{[1
]}

Hodi, F. Stephen, Jr. ^{[10
]}

Kelley, Mark C. ^{[11
]}

Khushalani, Nikhil I. ^{[12
]}

Kudchadkar, Ragini R. ^{[13
]}

Lange, Julie R. ^{[14
]}

Lind, Anne ^{[15
,16
]}

Martini, Mary C. ^{[17
]}

Olszanski, Anthony J. ^{[18
]}

Pruitt, Scott K. ^{[19
]}

Ross, Merrick I. ^{[20
]}

Swetter, Susan M. ^{[21
]}

Tanabe, Kenneth K. ^{[22
]}

Thompson, John A. ^{[23
]}

Trisal, Vijay ^{[24
]}

Urist, Marshall M. ^{[25
]}

McMillian, Nicole ^{[26
]}

Ho, Maria ^{[26
]}

机构：

[1] Mem Sloan Kettering Canc Ctr, New York, NY 10065 USA

[2] Univ Utah, Huntsman Canc Inst, Salt Lake City, UT 84112 USA

[3] Univ Michigan, Comprehens Canc Ctr, Ann Arbor, MI 48109 USA

[4] Ohio State Univ, Ctr Comprehens Canc, James Canc Hosp, Columbus, OH 43210 USA

[5] Solove Res Inst, Columbus, OH USA

[6] UCSF, Helen Diller Family Comprehens Canc Ctr, San Francisco, CA USA

[7] Univ Nebraska Med Ctr, UNMC Eppley Canc Ctr, Omaha, NE USA

[8] Univ Tennessee, Hlth Sci Ctr, St Jude Childrens Res Hosp, Knoxville, TN 37996 USA

[9] Aim Melanoma, Plano, TX USA

[10] Dana Farber Brigham & Womens Canc Ctr, Boston, MA USA

[11] Vanderbilt Ingram Canc Ctr, Nashville, TN USA

[12] Roswell Pk Canc Inst, Buffalo, NY USA

[13] H Lee Moffitt Canc Ctr & Res Inst, Tampa, FL USA

[14] Johns Hopkins, Sidney Kimmel Comprehens Canc Ctr, Baltimore, MD USA

[15] Barnes Jewish Hosp, Siteman Canc Ctr, St Louis, MO USA

[16] Washington Univ, Sch Med, St Louis, MO 63130 USA

[17] Northwestern Univ, Robert H Lurie Comprehens Canc Ctr, Evanston, IL 60208 USA

[18] Fox Chase Canc Ctr, Philadelphia, PA USA

[19] Duke Canc Inst, Durham, NC USA

[20] Univ Texas MD Anderson Canc Ctr, Houston, TX USA

[21] Stanford Canc Inst, Stanford, CA USA

[22] Massachusetts Gen Hosp, Ctr Canc, Boston, MA 02114 USA

[23] Fred Hutchinson Canc Res Ctr, Seattle Canc Care Alliance, Seattle, WA USA

[24] City Hope Comprehens Canc Ctr, Duarte, CA USA

[25] Univ Alabama, Birmingham Comprehens Canc Ctr, Tuscaloosa, AL 35487 USA

[26] Natl Comprehens Canc Network, Ft Washington, PA USA

来源：

JOURNAL OF THE NATIONAL COMPREHENSIVE CANCER NETWORK | 2013年 / 11卷 / 04期

关键词：

LYMPH-NODE BIOPSY; POSITRON-EMISSION-TOMOGRAPHY; COOPERATIVE-ONCOLOGY-GROUP; HIGH-RISK MELANOMA; COMPUTED-TOMOGRAPHY; OPEN-LABEL; METASTATIC MELANOMA; INITIAL EVALUATION; ADJUVANT THERAPY; PEGYLATED INTERFERON-ALPHA-2B;

D O I：

10.6004/jnccn.2013.0055

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 [肿瘤学];

摘要：

The NCCN Guidelines for Melanoma provide multidisciplinary recommendations on the clinical management of patients with melanoma. This NCCN Guidelines Insights report highlights notable recent updates. Foremost of these is the exciting addition of the novel agents ipilimumab and vemurafenib for treatment of advanced melanoma. The NCCN panel also included imatinib as a treatment for KIT-mutated tumors and pegylated interferon alfa-2b as an option for adjuvant therapy. Also important are revisions to the initial stratification of early-stage lesions based on the risk of sentinel lymph node metastases, and revised recommendations on the use of sentinel lymph node biopsy for low-risk groups. Finally, the NCCN panel reached clinical consensus on clarifying the role of imaging in the workup of patients with melanoma. (JNCCN 2013;11:395-407)

引用

页码：395 / 407

页数：13

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