Immunofluorescence assay for serologic diagnosis of SARS

被引：45

作者：

Chan, PKS ^{[1
]}

Ng, KC ^{[1
]}

Chan, RCW ^{[1
]}

Lam, RKY ^{[1
]}

Chow, VCY ^{[1
]}

Hui, MM ^{[1
]}

Wu, A ^{[1
]}

Lee, N ^{[1
]}

Yap, FHY ^{[1
]}

Cheng, FWT ^{[1
]}

Sung, JJY ^{[1
]}

Tam, JS ^{[1
]}

机构：

[1] Chinese Univ Hong Kong, Prince Wales Hosp, Dept Microbiol, Fac Med, Sha Tin, Hong Kong, Peoples R China

来源：

EMERGING INFECTIOUS DISEASES | 2004年 / 10卷 / 03期

关键词：

D O I：

10.3201/eid1003.030493

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

We evaluated an indirect immunofluorescence assay based on virus-infected cells for detecting anti-severe acute respiratory syndrome-associated coronavirus (SARS-CoV) immunoglobulin (Ig) G antibody. All confirmed SARS cases demonstrated seroconversion or fourfold rise in IgG antibody titer; no control was positive. Sensitivity and specificity of this assay were both 100%. Immunofluorescence assay can ascertain the status of SARS-CoV infection.

引用

页码：530 / 532

页数：3

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