Novel conversion of thiols into disulfides, via S-nitrosothiol intermediates using trichloronitromethane

被引：36

作者：

Demir, AS ^{[1
]}

Igdir, AC ^{[1
]}

Mahasneh, AS ^{[1
]}

机构：

[1] Middle E Tech Univ, Dept Chem, TR-06531 Ankara, Turkey

来源：

TETRAHEDRON | 1999年 / 55卷 / 42期

关键词：

disulfides; thionitroso compounds; thiols; nitroso compounds;

D O I：

10.1016/S0040-4020(99)00722-X

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

An efficient oxidative coupling of thiols to give disulfides via thionitrite (S-nitrosothiol) intermediate is described using trichloronitromethane as an efficient reagent in organic solvents and water. Cysteine and glutathione are converted into the corresponding disulfides in water in high yields. (C) 1999 Elsevier Science Ltd. All rights reserved.

引用

页码：12399 / 12404

页数：6

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