Electrochemical determination diethylstilbestrol by a multi-walled carbon nanotube/cobalt phthalocyanine film electrode

An analytical methodology for determination of diethylstilbestrol (DES) based on electrochemical response of this compound on glassy carbon electrode modified with gold nanoparticules (AuNPTs), multiwall carbon nanotubes (MWCNTs) and cobalt phtolocyanine (CoPc) was proposed. The modified electrode catalysed the electrochemical oxidation of DES and also improved the sensitivity in comparison with unmodified electrode. The experimental conditions were optimized and also the kinetic electrochemical parameters were also evaluated. From square wave voltammograms, the calibration curve for DES determination were obtained and the calculated detection and quantification limits were equal to 1.99 x 10(-7) mol L-1 and the 6.64 x 10(-7) mol L-1, respectively. The proposed electroanalytical methodology was successfully applied for DES determination in water, and meat with satisfactory results, showing that fabricated sensor has potential do be applied in laboratory practices for DES determination in complex samples. (C) 2016 Elsevier B.V. All rights reserved.