Using Predictive Biomarkers to Select Patients With Advanced Colorectal Cancer for Treatment With Epidermal Growth Factor Receptor Antibodies

被引:72
作者
Wong, Rachel [1 ]
Cunningham, David [1 ]
机构
[1] Royal Marsden Hosp, Dept Med, Sutton, Surrey, England
关键词
D O I
10.1200/JCO.2008.19.5024
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
引用
收藏
页码:5668 / 5670
页数:3
相关论文
共 27 条
[1]   Wild-type KRAS is required for panitumumab efficacy in patients with metastatic colorectal cancer [J].
Amado, Rafael G. ;
Wolf, Michael ;
Peeters, Marc ;
Van Cutsem, Eric ;
Siena, Salvatore ;
Freeman, Daniel J. ;
Juan, Todd ;
Sikorski, Robert ;
Suggs, Sid ;
Radinsky, Robert ;
Patterson, Scott D. ;
Chang, David D. .
JOURNAL OF CLINICAL ONCOLOGY, 2008, 26 (10) :1626-1634
[2]  
[Anonymous], 2008, Journal of Clinical Oncology
[3]  
Baron AT, 2003, CANCER EPIDEM BIOMAR, V12, P103
[4]   Oncogenic activation of the RAS/RAF signaling pathway impairs the response of metastatic colorectal cancers to anti-epidermal growth factor receptor antibody therapies [J].
Benvenuti, Silvia ;
Sartore-Bianchi, Andrea ;
Di Nicolantonio, Federica ;
Zanon, Carlo ;
Moroni, Mauro ;
Veronese, Silvio ;
Siena, Salvatore ;
Bardelli, Alberto .
CANCER RESEARCH, 2007, 67 (06) :2643-2648
[5]   Bleomycin in testicular cancer: Will pharmacogenomics improve treatment regimens? [J].
Bokemeyer, Carsten .
JOURNAL OF CLINICAL ONCOLOGY, 2008, 26 (11) :1783-1785
[6]   Cetuximab shows activity in colorectal cancer patients with tumors that do not express the epidermal growth factor receptor by immunohistochemistry [J].
Chung, KY ;
Shia, J ;
Kemeny, NE ;
Shah, M ;
Schwartz, GK ;
Tse, A ;
Hamilton, A ;
Pan, D ;
Schrag, D ;
Schwartz, L ;
Klimstra, DS ;
Fridman, D ;
Kelsen, DP ;
Saltz, LB .
JOURNAL OF CLINICAL ONCOLOGY, 2005, 23 (09) :1803-1810
[7]   Cetuximab monotherapy and cetuximab plus irinotecan in irinotecan-refractory metastatic colorectal cancer [J].
Cunningham, D ;
Humblet, Y ;
Siena, S ;
Khayat, D ;
Bleiberg, H ;
Santoro, A ;
Bets, D ;
Mueser, M ;
Harstrick, A ;
Verslype, C ;
Chau, I ;
Van Cutsem, E .
NEW ENGLAND JOURNAL OF MEDICINE, 2004, 351 (04) :337-345
[8]   Wild-Type BRAF Is Required for Response to Panitumumab or Cetuximab in Metastatic Colorectal Cancer [J].
Di Nicolantonio, Federica ;
Martini, Miriam ;
Molinari, Francesca ;
Sartore-Bianchi, Andrea ;
Arena, Sabrina ;
Saletti, Piercarlo ;
De Dosso, Sara ;
Mazzucchelli, Luca ;
Frattini, Milo ;
Siena, Salvatore ;
Bardelli, Alberto .
JOURNAL OF CLINICAL ONCOLOGY, 2008, 26 (35) :5705-5712
[9]   PTEN loss of expression predicts cetuximab efficacy in metastatic colorectal cancer patients [J].
Frattini, M. ;
Saletti, P. ;
Romagnani, E. ;
Martin, V. ;
Molinari, F. ;
Ghisletta, M. ;
Camponovo, A. ;
Etienne, L. L. ;
Cavalli, F. ;
Mazzucchelli, L. .
BRITISH JOURNAL OF CANCER, 2007, 97 (08) :1139-1145
[10]   Phosphorylation status of epidermal growth factor receptor is closely associated with responsiveness to gefitinib in pulmonary adenocarcinoma [J].
Hijiya, Naoki ;
Miyawaki, Michiyo ;
Kawahara, Katsunobu ;
Akamine, Shinji ;
Tsuji, Koh-Ichi ;
Kadota, Jun-Ichi ;
Akizuki, Shin'ichiro ;
Uchida, Tomohisa ;
Matsuura, Keiko ;
Tsukamoto, Yoshiyuki ;
Moriyama, Masatsugu .
HUMAN PATHOLOGY, 2008, 39 (03) :316-323