Selectivity enhancement in capillary electrophoresis using non-aqueous media

Efficiency and selectivity are two important parameters in separation science in order to facilitate resolution of solutes. High efficiencies are easily obtained using capillary electrophoresis. Selectivity can be improved using different additives like surfactants or cyclodextrins. Recently, it has been shown that also non-aqueous capillary electrophoresis provides large improvements in selectivity and without the use of the above-mentioned additives.