Oxygen-releasing biomaterials for tissue engineering

被引：143

作者：

Camci-Unal, Gulden ^{[1
,2
]}

Alemdar, Neslihan ^{[1
,2
]}

Annabi, Nasim ^{[1
,2
,3
]}

Khademhosseini, Ali ^{[1
,2
,3
]}

机构：

[1] Harvard Univ, Brigham & Womens Hosp, Ctr Biomed Engn, Dept Med,Med Sch, Cambridge, MA 02139 USA

[2] MIT, Harvard Mit Div Hlth Sci & Technol, Cambridge, MA 02139 USA

[3] Harvard Univ, Wyss Inst Biol Inspired Engn, Boston, MA 02115 USA

来源：

POLYMER INTERNATIONAL | 2013年 / 62卷 / 06期

基金：

美国国家科学基金会; 美国国家卫生研究院;

关键词：

oxygen-releasing biomaterials; peroxides; cell survival; tissue engineering; HYDROGEN-PEROXIDE; CALCIUM PEROXIDE; CARDIAC TISSUE; DECOMPOSITION; SCAFFOLDS; TRANSPORT; KINETICS; GROWTH;

D O I：

10.1002/pi.4502

中图分类号：

O63 [高分子化学（高聚物）];

学科分类号：

070305 [高分子化学与物理];

摘要：

Due to the increasing demand to generate thick and vascularized tissue-engineered constructs, novel strategies are currently being developed. An emerging example is the generation of oxygen-releasing biomaterials to tackle mass transport and diffusion limitations within engineered tissue constructs. Biomaterials containing oxygen-releasing molecules can be fabricated in various forms, such as hybrid thin films, microparticles or three dimensional scaffolds. In this perspective, we summarize various oxygen-releasing reagents and their potential applications in regenerative engineering. Moreover, we review the main approaches for fabricating oxygen-releasing biomaterials for a range of tissue engineering applications. (c) 2013 Society of Chemical Industry

引用

页码：843 / 848

页数：6

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