Lack of MERS Coronavirus Neutralizing Antibodies in Humans, Eastern Province, Saudi Arabia

被引：42

作者：

Gierer, Stefanie ^{[1
]}

Hofmann-Winkler, Heike ^{[1
]}

Albuali, Waleed H. ^{[2
]}

Bertram, Stephanie ^{[1
]}

Al-Rubaish, Abdullah M. ^{[2
]}

Yousef, Abdullah A. ^{[2
]}

Al-Nafaie, Awatif N. ^{[2
]}

Al-Ali, Amein K. ^{[2
]}

Obeid, Obeid E. ^{[2
]}

Alkharsah, Khaled R. ^{[2
]}

Poehlmann, Stefan ^{[1
]}

机构：

[1] German Primate Ctr, D-37077 Gottingen, Germany

[2] Univ Dammam, Dammam, Saudi Arabia

来源：

EMERGING INFECTIOUS DISEASES | 2013年 / 19卷 / 12期

关键词：

INFECTIONS; RECEPTOR; ENTRY;

D O I：

10.3201/eid1912.130701

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

We used a lentiviral vector bearing the viral spike protein to detect neutralizing antibodies against Middle East respiratory syndrome coronavirus (MERS-CoV) in persons from the Eastern Province of Saudi Arabia. None of the 268 samples tested displayed neutralizing activity, which suggests that MERS-CoV infections in humans are infrequent in this province.

引用

页码：2034 / 2036

页数：3

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