Development, trafficking, and function of memory T-cell subsets

被引:113
作者
Lefrancois, Leo [1 ]
机构
[1] Univ Connecticut, Ctr Hlth, Dept Immunol, Farmington, CT 06107 USA
关键词
D O I
10.1111/j.0105-2896.2006.00393.x
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
The precise mechanisms that govern memory T-cell lineage commitment during an immune response continue to be the subject of intense scrutiny. The existence of memory T-cell subsets defined by location, function, and phenotype adds an additional layer of complexity to the overall memory T-cell population. In this review, the integration of memory subset development and migration and the functional consequences of specific tissue localization are discussed.
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页码:93 / 103
页数:11
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