Coupling RNA polymerase II transcription with pre-mRNA processing

被引：197

作者：

Bentley, D ^{[1
]}

机构：

[1] Univ Colorado, Sci Ctr B121, Dept Biochem & Mol Genet, Denver, CO 80262 USA

来源：

CURRENT OPINION IN CELL BIOLOGY | 1999年 / 11卷 / 03期

关键词：

D O I：

10.1016/S0955-0674(99)80048-9

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

How are transcription and processing of mRNA precursors co-ordinated The past two years has witnessed exciting insights into the mechanism which targets the mRNA processing machinery to RNA polymerase II (pol II) transcription complexes and closely integrates processing with transcription. Protein-protein contacts have been discovered between the pol II transcription machinery and RNA processing factors; furthermore, a unique domain of pol II has been identified that not only recruits processing factors but also controls their activity.

引用

页码：347 / 351

页数：5

共 51 条

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