The lethal (2) giant larva (l(2)gl), a recessive oncogene, is required during embryonic and post-embryonic development in Drosophila

被引:8
作者
Baek, KH
Hanratty, WP
机构
[1] Division of Genetics, Harvard Medical School
[2] s Hospital, Boston, MA 02115
[3] Department of Biology, Indiana University, Bloomington
关键词
l(2)gl; oncogene; neoplasm; imaginal disc; tumor; mgl-1; SUPPRESSOR GENE L(2)GL; MOUSE HOMOLOG; MELANOGASTER;
D O I
10.1016/S0304-3835(96)04535-1
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Recessive oncogenes have genetic functions important for the regulation of tissue growth and differentiation. Defining the role of these genes in normal developmental and physiological processes is important to the development of the accurate models of the normal regulation of growth and differentiation: We report here a genetic analysis of the requirement for the lethal (2) giant larva function during development. The results demonstrate that the lethal (2) giant larva function is required during embryonic and post-embryonic development to maintain the normal developmental capacity. (C) 1997 Elsevier Science Ireland Ltd.
引用
收藏
页码:233 / 238
页数:6
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