Familial clustering of intracerebral hemorrhage: A prospective study in north Carolina

被引:22
作者
Alberts, MJ [1 ]
McCarron, MO [1 ]
Hoffmann, KL [1 ]
Graffagnino, C [1 ]
机构
[1] Duke Univ, Med Ctr, Dept Med, Div Neurol, Durham, NC 27710 USA
关键词
intracerebral hemorrhage; familial clustering;
D O I
10.1159/000048609
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 ; 120402 ;
摘要
Few studies have assessed the frequency of familial clustering in intracerebral hemorrhage (ICH). Of 144 patients with ICH prospectively assessed, 14 (9.8%) had a positive family history of ICH (FH+). Four pedigrees had more than two affected family members. Comparisons between FH+ and FH- probands demonstrated no significant differences in race, age, sex, ICH type or location. An underlying genetic etiology may account for familial clustering in some ICH patients. Copyright (C) 2002 S. Karger AG, Basel.
引用
收藏
页码:18 / 21
页数:4
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