Antihepatotoxic effect of Nymphaea stellata willd., against carbon tetrachloride-induced hepatic damage in albino rats

被引：84

作者：

Bhandarkar, MR ^{[1
]}

Khan, A ^{[1
]}

机构：

[1] Nagpur Univ, Dept Biochem, Nagpur 440010, Maharashtra, India

来源：

JOURNAL OF ETHNOPHARMACOLOGY | 2004年 / 91卷 / 01期

关键词：

anti-hepatotoxic; carbon tetrachloride; Nymphaea stellata willd;

D O I：

10.1016/j.jep.2003.11.020

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Nymphaea stellata willd., a medicinal plant mentioned in Ayurveda for the treatment of liver disorders, has not been subjected to systematic scientific investigations to asses its hepatoprotective effects. Therefore, the present study was undertaken to investigate the hepatoprotective activity of extract of Nymphaea stellata willd., flower against carbon tetrachloride-induced hepatic damage in albino rats. The oral administration of varying dosage of extract of Nymphaea stellata willd., flower to rats for 10 days afforded the good hepatoprotection against carbon tetrachloride-induced elevation in serum marker enzymes, serum bilimbin, liver lipid peroxidation and reduction in liver glutathione, liver glutathione peroxidase, glycogen, superoxide dismutase and catalase activity. (C) 2003 Published by Elsevier Ireland Ltd.

引用

页码：61 / 64

页数：4

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