Hyperbaric oxygen as an adjunct in zygomycosis: Randomized controlled trial in a murine model

被引：36

作者：

Barratt, DM

Van Meter, K

Asmar, P

Nolan, T

Trahan, C

Garcia-Covarrubias, L

Metzinger, SE

机构：

[1] Louisiana State Univ, Dept Med, Sect Emergency Med & Hyperbar Med, New Orleans, LA 70112 USA

[2] Louisiana State Univ, Dept Otolaryngol Head & Neck Surg, New Orleans, LA 70112 USA

[3] Baromed Res Inst, New Orleans, LA 70114 USA

[4] Univ S Carolina, Dept Surg, Columbia, SC 29203 USA

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 2001年 / 45卷 / 12期

关键词：

D O I：

10.1128/AAC.45.12.3601-3602.2001

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Zygomycosis was induced by injecting CD-1 mice with 5 mg of intraperitoneal deferoxamine and then 10(6) CFU of intravenous and intrasinus Rhizopus arrhizus. The addition of hyperbaric oxygen (2.0 atm absolute twice daily) to amphotericin B did not improve survival over that achieved with amphotericin B and placebo air treatments.

引用

页码：3601 / 3602

页数：2

共 14 条

[1] EFFECTS OF IRON AND DESFERRIOXAMINE ON RHIZOPUS INFECTION [J].