Cost-utility of the cochlear implant in adults -: A meta-analysis

Objective: To conduct a meta-analysis of the cost-utility of the cochlear implant in adult;. Data Sources: MEDLINE literature search, review of article bibliographies, and consultation with experts. Study Selection: Studies that reported (I) data on adults (age greater than or equal to 18 years) with bilateral, postlingual, profound deafness; (2) a health-utility gain from cochlear implantation on a scale from 0.00 (death) to 1.00 (perfect health! (3) a cost-utility ratio in terms of dollars per quality-adjusted life-year (QALY); and (4) at least I conventional statistical parameter tie, SDI 95% confidence interval [CI], or P value). Data Extraction: From each study, we extracted the number of subjects, study design, health-utility instrument used, health-utility associated with profound deafness, health-utility gain from cochlear implantation, cost-utility of cochlear implantation, and reported statistical parameters. Data Synthesis: Weighted averages were calculated using a statistical weight of I per variance. Pooling 9 reports (n = 619), the health-utility of profoundly deaf adults without cochlear implants was 0.54 (95% CI, 0.52-0.56). Pooling 7 studies (n = 511), the health-utility of profoundly deaf adults after cochlear implantation was 0.80 (95% Ct, 0.78-0.82). This improvement of 0.26 in health-utility resulted in a cost-utility ratio of $12 787 per QALY. Conclusions: Profound deafness in adults results in a substantial health-utility loss, Over half of that loss is restored after cochlear implantation, yielding a cost-utility ratio of $12 787 per QALY. This figure compares favorably with medical and surgical interventions that are commonly covered by third-party payers in the United States today.