Convenient intermediates for the preparation of C-4 modified derivatives of pyrimidine nucleosides

被引：32

作者：

Miah, A ^{[1
]}

Reese, CB ^{[1
]}

Song, QL ^{[1
]}

机构：

[1] UNIV LONDON KINGS COLL,DEPT CHEM,LONDON WC2R 2LS,ENGLAND

来源：

NUCLEOSIDES & NUCLEOTIDES | 1997年 / 16卷 / 1-2期

关键词：

D O I：

10.1080/07328319708002521

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

4-(4-Nitrophenoxy)-1-(beta-D-ribofuranosyl)pyrimidin-2(1H)-one 15, 5-methyl-4-(1,2,4-triazol-1-yl)-1-(beta-D-2-deoxyribofuranosyl 7a and 4-(4-nitrophenoxy)-1-(beta-D-2-deoxyribofuranosyl)pyrimidin-2(1H)-one 17a, respectively, have been prepared and are recommended as reactive intermediates for the preparation of derivatives of uridine, thymidine and 2'-deoxyuridine which are modified at C-4.

引用

页码：53 / 65

页数：13

共 20 条

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