Supramolecular formation of porphyrins and antibodies

被引:9
作者
Harada, A [1 ]
Yamaguchi, H [1 ]
Oka, F [1 ]
Kamachi, M [1 ]
机构
[1] Osaka Univ, Grad Sch Sci, Osaka 5600043, Japan
来源
SCANNING AND FORCE MICROSCOPIES FOR BIOMEDICAL APPLICATIONS, PROCEEDINGS OF | 1999年 / 3607卷
关键词
AFM; biosensor; antibodies; porphyrins; supramolecules;
D O I
10.1117/12.350627
中图分类号
R446 [实验室诊断]; R-33 [实验医学、医学实验];
学科分类号
1001 ;
摘要
The supramolecular formation of tetracarboxyphenylporphyrin(TCPP) and anti-TCPP antibody was studied by a biosensor (BIAcore) and atomic Force microscope (AFM). Results of BIAcore for the complexes of antibodies with TCPP suggested the supramolecular formation with the binding of two antibodies and a porphyrin molecule. AFM images of cyclic trimer, pentamer and linear oligomers constituted by antibodies and porphyrin dimers were obtained.
引用
收藏
页码:126 / 135
页数:10
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