Alkaloids of Sternbergia clusiana and their analgesic effects

被引：33

作者：

Tanker, M

Citoglu, G

Gumusel, B

Sener, B

机构：

[1] HACETTEPE UNIV, FAC PHARM, DEPT PHARMACOGNOSY, TR-06100 ANKARA, TURKEY

[2] HACETTEPE UNIV, FAC PHARM, DEPT PHARMACOL, TR-06100 ANKARA, TURKEY

[3] GAZI UNIV, FAC PHARM, DEPT PHARMACOGNOSY, TR-06100 ANKARA, TURKEY

来源：

INTERNATIONAL JOURNAL OF PHARMACOGNOSY | 1996年 / 34卷 / 03期

关键词：

analgesic activity; lycorine; haemanthidine; modified Koster's test; Amaryllidaceae; Sternbergia clusiana (Ker-Gawl) Ker Gawl. ex Sprengel;

D O I：

10.1076/phbi.34.3.194.13207

中图分类号：

Q94 [植物学];

学科分类号：

071001 [植物学];

摘要：

Sternbergia clusiana of Turkish origin has yielded four alkaloids, lycorine, haemanthamine, haemanthidine, and tazettine. The alkaloids were separated using chromatographic methods and purified by crystallization. Their structures have been elucidated by spectroscopic studies. The analgesic activity of lycorine and haemanthidine was determined using modified Koster's test. Lycorine and haemanthidine showed a significant analgesic effect. The analgesic activities of lycorine and haemanthidine are higher than those of aspirin.

引用

页码：194 / 197

页数：4

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