ADHD, stimulant treatment in childhood and subsequent substance abuse in adulthood - A naturalistic long-term follow-up study

被引：101

作者：

Dalsgaard, Soren ^{[1
,2
,3
,4
,5
,6
,7
]}

Mortensen, Preben Bo ^{[1
]}

Frydenberg, Morten ^{[8
]}

Thomsen, Per Hove ^{[2
]}

机构：

[1] Aarhus Univ, Natl Ctr Register Based Res, Dept Econ & Business, Sch Business & Social Sci, DK-8210 Aarhus V, Denmark

[2] Aarhus Univ Hosp, Ctr Child & Adolescent Psychiat, DK-8000 Aarhus, Denmark

[3] Aarhus Univ, Lundbeck Fdn Initiat Integrat Psychiat Res, iPSYCH, DK-8210 Aarhus V, Denmark

[4] Univ Copenhagen, Aarhus, Denmark

[5] Aarhus Univ, Lundbeck Fdn Initiat Integrat Psychiat Res, iPSYCH, Copenhagen, Denmark

[6] Univ Copenhagen, Copenhagen, Denmark

[7] Hosp Telemark, Dept Child & Adolescent Psychiat, Kragero, Norway

[8] Aarhus Univ, Sect Biostat, Dept Publ Hlth, DK-8210 Aarhus V, Denmark

来源：

ADDICTIVE BEHAVIORS | 2014年 / 39卷 / 01期

关键词：

Attention-deficit/hyperactivity disorder (ADHD); Substance use disorder; Alcohol; Epidemiology; Methylphenidate; Pharmacoepidemiology; ATTENTION-DEFICIT/HYPERACTIVITY DISORDER; DEFICIT HYPERACTIVITY DISORDER; CIGARETTE-SMOKING; CHILDREN; RISK; DRUG; PREVALENCE; PREDICTORS; INITIATION; CIRCUITRY;

D O I：

10.1016/j.addbeh.2013.09.002

中图分类号：

B849 [应用心理学];

学科分类号：

040203 ;

摘要：

The purpose of the study was to estimate the risk of substance use disorder (SUD) and alcohol abuse in adulthood among children and adolescents with attention-deficit hyperactivity disorder (ADHD) compared to the background population. Furthermore, to examine whether the age at initiation and duration of stimulant treatment in childhood predicts SUD and alcohol abuse in adulthood. 208 youths with ADHD (183 boys; 25 girls) were followed prospectively. Diagnoses of SUD and alcohol abuse were obtained from The Danish Psychiatric Central Register. The relative risk (RR) of SUD and alcohol abuse for cases with ADHD, compared to the background population was 7.7 (43-13.9) and 52 (2.9-9.4), respectively. Female gender, conduct disorder in childhood and older age at initiation of stimulant treatment increased the risk of later SUD and alcohol abuse. Our results warrant increased focus on the possibly increased risk of substance abuse in females with ADHD compared to males with ADHD. (C) 2013 Elsevier Ltd. All rights reserved.

引用

页码：325 / 328

页数：4

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