Pleiotropic Effects of PCSK9 (Proprotein Convertase Subtilisin/Kexin Type 9) Inhibitors?

被引:28
作者
Bittner, Vera [1 ,2 ]
机构
[1] Univ Alabama Birmingham, Dept Med, 701 19th St South,LHRB 310, Birmingham, AL 35294 USA
[2] Univ Alabama Birmingham, Div Cardiovasc Dis, 701 19th St South,LHRB 310, Birmingham, AL 35294 USA
关键词
lipids; lipoproteins; PCSK9;
D O I
10.1161/CIRCULATIONAHA.116.023687
中图分类号
R5 [内科学];
学科分类号
100201 [内科学];
摘要
[No abstract available]
引用
收藏
页码:1695 / 1696
页数:2
相关论文
共 5 条
[1]
PCSK9 in relation to coronary plaque inflammation: Results of the ATHEROREMO-IVUS study [J].
Cheng, Jin M. ;
Oemrawsingh, Rohit M. ;
Garcia-Garcia, Hector M. ;
Boersma, Eric ;
van Geuns, Robert-Jan ;
Serruys, Patrick W. ;
Kardys, Isabella ;
Akkerhuis, K. Martijn .
ATHEROSCLEROSIS, 2016, 248 :117-122
[2]
Efficiency and Safety of Proprotein Convertase Subtilisin/Kexin 9 Monoclonal Antibody on Hypercholesterolemia: A Meta-Analysis of 20 Randomized Controlled Trials [J].
Li, Chuanwei ;
Lin, Ling ;
Zhang, Wen ;
Zhou, Liang ;
Wang, Hongyong ;
Luo, Xiaoli ;
Luo, Hao ;
Cai, Yue ;
Zeng, Chunyu .
JOURNAL OF THE AMERICAN HEART ASSOCIATION, 2015, 4 (06) :e001937
[3]
Proprotein Convertase Subtilisin/Kexin Type 9 Monoclonal Antibodies for Acute Coronary Syndrome A Narrative Review [J].
Navarese, Eliano P. ;
Kolodziejczak, Michalina ;
Kereiakes, Dean J. ;
Tantry, Udaya S. ;
O'Connor, Christopher ;
Gurbel, Paul A. .
ANNALS OF INTERNAL MEDICINE, 2016, 164 (09) :600-+
[4]
PCSK9 inhibition-mediated reduction in Lp(a) with evolocumab: an analysis of 10 clinical trials and the LDL receptor's role [J].
Raal, Frederick J. ;
Giugliano, Robert P. ;
Sabatine, Marc S. ;
Koren, Michael J. ;
Blom, Dirk ;
Seidah, Nabil G. ;
Honarpour, Narimon ;
Lira, Armando ;
Xue, Allen ;
Chiruvolu, Padmaja ;
Jackson, Simon ;
Di, Mei ;
Peach, Matthew ;
Somaratne, Ransi ;
Wasserman, Scott M. ;
Scott, Rob ;
Stein, Evan A. .
JOURNAL OF LIPID RESEARCH, 2016, 57 (06) :1086-1096
[5]
PCSK9 is a critical regulator of the innate immune response and septic shock outcome [J].
Walley, Keith R. ;
Thain, Katherine R. ;
Russell, James A. ;
Reilly, Muredach P. ;
Meyer, Nuala J. ;
Ferguson, Jane F. ;
Christie, Jason D. ;
Nakada, Taka-aki ;
Fjell, Chris D. ;
Thair, Simone A. ;
Cirstea, Mihai S. ;
Boyd, John H. .
SCIENCE TRANSLATIONAL MEDICINE, 2014, 6 (258) :258ra143