Sterilization techniques for biodegradable scaffolds in tissue engineering applications

被引：249

作者：

Dai, Zheng ^{[1
]}

Ronholm, Jennifer ^{[2
]}

Tian, Yiping ^{[1
]}

Sethi, Benu ^{[1
]}

Cao, Xudong ^{[1
]}

机构：

[1] Univ Ottawa, Dept Chem & Biol Engn, 161 Louis Pasteur, Ottawa, ON K1N 6N5, Canada

[2] Univ Ottawa, Dept Biochem Microbiol & Immunol, Ottawa, ON, Canada

来源：

JOURNAL OF TISSUE ENGINEERING | 2016年 / 7卷

关键词：

Biodegradable scaffolds; tissue engineering; sterilization; biomaterials; ETHYLENE-OXIDE STERILIZATION; FLUID CARBON-DIOXIDE; MECHANICAL-PROPERTIES; GAMMA-IRRADIATION; E-BEAM; HYDROGEN-PEROXIDE; THERMAL-TREATMENT; PERACETIC-ACID; IN-VITRO; RADIATION;

D O I：

10.1177/2041731416648810

中图分类号：

Q813 [细胞工程];

学科分类号：

100113 [医学细胞生物学];

摘要：

Biodegradable scaffolds have been extensively studied due to their wide applications in biomaterials and tissue engineering. However, infections associated with in vivo use of these scaffolds by different microbiological contaminants remain to be a significant challenge. This review focuses on different sterilization techniques including heat, chemical, irradiation, and other novel sterilization techniques for various biodegradable scaffolds. Comparisons of these techniques, including their sterilization mechanisms, post-sterilization effects, and sterilization efficiencies, are discussed.

引用

页数：13

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