Onset of multiple sclerosis associated with anti-TNF therapy

被引:232
作者
Sicotte, NL [1 ]
Voskuhl, RR [1 ]
机构
[1] Univ Calif Los Angeles, Sch Med, Dept Neurol, Div Brain Mapping, Los Angeles, CA USA
关键词
D O I
10.1212/WNL.57.10.1885
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Therapies aimed at inhibiting tumor necrosis factor (TNF) a proinflammatory cytokine implicated in autoimmune disease are effective, especially for rheumatoid arthritis. We report a patient with new onset MS closely associated with the initiation of anti-TNF therapy for juvenile rheumatoid arthritis. It is possible that the inhibition of TNF triggered MS in this individual.
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页码:1885 / 1888
页数:4
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