The current role of neoadjuvant chemotherapy in the management of cervical carcinoma

被引：66

作者：

Gonzalez-Martin, Antonio ^{[1
,2
]}

Gonzalez-Cortijo, Lucia ^{[2
]}

Carballo, Natalia ^{[3
]}

Garcia, Juan F. ^{[4
]}

Lapuente, Fernando ^{[5
]}

Rojo, Alejandro ^{[4
]}

Chiva, Luis M. ^{[5
]}

机构：

[1] Hosp Ramon & Cajal, Med Oncol Serv, E-28034 Madrid, Spain

[2] MD Anderson Int Espana, Dept Med Oncol, Madrid, Spain

[3] MD Anderson Int Espana, Dept Radiat Oncol, Madrid, Spain

[4] MD Anderson Int Espana, Dept Pathol, Madrid, Spain

[5] MD Anderson Int Espana, Dept Gynecol Oncol, Madrid, Spain

来源：

GYNECOLOGIC ONCOLOGY | 2008年 / 110卷 / 03期

关键词：

neoadjuvant chemotherapy; cervical carcinoma; chemotherapy; meta-analysis;

D O I：

10.1016/j.ygyno.2008.05.012

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

The role of neoadjuvant chemotherapy (NACT) in cervical cancer has been a matter of investigation over the last 20 years. A systematic review and meta-analysis of individual patient data (IPD) demonstrated that NACT followed by surgery is superior to radiotherapy alone in terms of overall survival. However, in spite of the results of the meta-analysis, NACT has not been adopted as the new standard of care. In the present paper, we review the reasons why NACT is still considered an investigational approach in cervical cancer. (C) 2008 Elsevier Inc. All rights reserved.

引用

页码：S36 / S40

页数：5

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