The role of functional neuroimaging in pediatric brain injury

被引:29
作者
Munson, S [1 ]
Schroth, E [1 ]
Ernst, M [1 ]
机构
[1] NIMH, NIH, Mood & Anxiety Disorders Program, Bethesda, MD 20892 USA
关键词
brain development; functional neuroimaging; brain injury; plasticity; vulnerability;
D O I
10.1542/peds.2005-0826
中图分类号
R72 [儿科学];
学科分类号
100202 ;
摘要
The aim of this article is to review empirical studies published in the last 10 years that used various functional neuroimaging techniques to assess pediatric patients with brain injury. Overall, these studies have demonstrated the ability of functional neuroimaging to offer unique information concerning the diagnosis, clinical outcome, and recovery mechanisms after pediatric brain injury. Future research using functional neuroimaging is recommended to better understand the functional reorganization and neurodevelopmental consequences resulting from brain injury. Such research might allow clinicians to design tailored early-intervention and rehabilitation programs to maximize the recovery process for pediatric patients. Limitations and advantages associated with the use of functional neuroimaging in pediatric populations are discussed.
引用
收藏
页码:1372 / 1381
页数:10
相关论文
共 54 条
[1]   Long-term sequelae of prefrontal cortex damage acquired in early childhood [J].
Anderson, SW ;
Damasio, H ;
Tranel, D ;
Damasio, AR .
DEVELOPMENTAL NEUROPSYCHOLOGY, 2000, 18 (03) :281-296
[2]   Predictive value of proton magnetic resonance spectroscopy in pediatric closed head injury [J].
Ashwal, S ;
Holshouser, BA ;
Shu, SK ;
Simmons, PL ;
Perkin, RM ;
Tomasi, LG ;
Knierim, DS ;
Sheridan, C ;
Craig, K ;
Andrews, GH ;
Hinshaw, DB .
PEDIATRIC NEUROLOGY, 2000, 23 (02) :114-125
[3]  
AUID K, 1995, PEDIATR NEUROL, V12, P323
[4]   Visual functional magnetic resonance imaging in patients with Sturge-Weber syndrome [J].
Bernal, B ;
Altman, N .
PEDIATRIC NEUROLOGY, 2004, 31 (01) :9-15
[5]   Neuroimaging in pediatric traumatic head injury: Diagnostic considerations and relationships to neurobehavioral outcome [J].
Bigler, ED .
JOURNAL OF HEAD TRAUMA REHABILITATION, 1999, 14 (04) :406-423
[6]  
Bookheimer SY, 2000, MENT RETARD DEV D R, V6, P161, DOI 10.1002/1098-2779(2000)6:3<161::AID-MRDD2>3.3.CO
[7]  
2-N
[8]   Developmental and lesion effects in brain activation during sentence comprehension and mental rotation [J].
Booth, JR ;
MacWhinney, B ;
Thulborn, KR ;
Sacco, K ;
Voyvodic, JT ;
Feldman, HM .
DEVELOPMENTAL NEUROPSYCHOLOGY, 2000, 18 (02) :139-169
[9]   Discussion of developmental plasticity: Factors affecting cognitive outcome after pediatric traumatic brain injury [J].
Chapman, SB ;
McKinnon, L .
JOURNAL OF COMMUNICATION DISORDERS, 2000, 33 (04) :333-344
[10]   Functional brain reorganization in children [J].
Chugani, HT ;
Muller, RA ;
Chugani, DC .
BRAIN & DEVELOPMENT, 1996, 18 (05) :347-356