Immunomodulatory activity of alcoholic extract of Mangifera indica L. in mice

被引：148

作者：

Makare, N ^{[1
]}

Bodhankar, S ^{[1
]}

Rangari, V ^{[1
]}

机构：

[1] Bharati Vidyapeeth Deemed Univ, Poona Coll Pharm, Pune 411038, Maharashtra, India

来源：

JOURNAL OF ETHNOPHARMACOLOGY | 2001年 / 78卷 / 2-3期

关键词：

Mangifera indica; Cell mediated immunity; humoral immunity; immunomodulatory;

D O I：

10.1016/S0378-8741(01)00326-9

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Mangifera indica Linn, a plant widely used in the traditional medicinal systems of India, has been reported to possess antiviral, antibacterial and anti-inflammatory activities. In the present study, the alcoholic extract of stem bark of Mangifera indica Linn (Extract I containing mangiferin 2.6%), has been investigated for its effect on cell mediated and humoral components of the immune system in mice. Administration of test extract I produced increase in humoral antibody (HA) titre and delayed type hypersensitivity (DTH) in mice. It is concluded that test extract I is a promising drug with immunostimulant properties. (C) 2001 Elsevier Science Ireland Ltd. All rights reserved.

引用

页码：133 / 137

页数：5

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