Intracellular signaling - Putting JAKs on the kinase MAP

被引：87

作者：

Winston, LA

Hunter, T

机构：

[1] Molec. Biol. and Virology Laboratory, Salk Inst. for Biological Studies, San Diego, CA 92037

来源：

CURRENT BIOLOGY | 1996年 / 6卷 / 06期

关键词：

D O I：

10.1016/S0960-9822(09)00445-X

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Tyrosine kinases of the JAK family are required for activation of bath STAT transcription factors and the ERK/MAP kinase pathway, suggesting a mechanism for the optimization of gene induction via the coordinate activation of multiple transcription factors.

引用

收藏

页码：668 / 671

页数：4

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