Hydrogen abstraction from neurotransmitters by active oxygen species facilitated by intramolecular hydrogen bonding in the radical intermediates

被引：17

作者：

Ohkubo, K

Moro-oka, Y

Fukuzumi, S

机构：

[1] Osaka Univ, SORST, JST, Grad Sch Engn,Dept Mat & Life Sci, Suita, Osaka 5650871, Japan

[2] Tokiwa Univ, Coll Community Dev, Mito, Ibaraki 3108585, Japan

来源：

ORGANIC & BIOMOLECULAR CHEMISTRY | 2006年 / 4卷 / 06期

关键词：

D O I：

10.1039/b600111d

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The reactivity of neurotransmitters toward hydrogen abstraction by an active oxygen species (the cumylperoxyl radical) is comparable to that of a strong antioxidant such as catechin due to the strong intramolecular hydrogen bonding, which has been successfully detected by ESR.

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页码：999 / 1001

页数：3

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