β-cell proliferation is the major source of new pancreatic β cells

被引：24

作者：

Dor, Y ^{[1
]}

机构：

[1] Hebrew Univ Jerusalem, Hadassah Med Sch, Dept Cellular Biochem & Human Genet, IL-91120 Jerusalem, Israel

来源：

NATURE CLINICAL PRACTICE ENDOCRINOLOGY & METABOLISM | 2006年 / 2卷 / 05期

关键词：

D O I：

10.1038/ncpendmet0187

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

New insulin-producing β cells are produced throughout adult life and could potentially be exploited in regenerative therapies for diabetes. Although pancreatic progenitor cell differentiation has been proposed to drivede novoβ-cell generation, this Viewpoint argues that new β cells arise from the proliferation of pre-existing β cells.

引用

页码：242 / 243

页数：2

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