Homoarginine - An independent marker of mortality in heart failure

被引:59
作者
Atzler, Dorothee [1 ]
Rosenberg, Mark [2 ]
Anderssohn, Maike [1 ]
Choe, Chi-un [3 ,4 ]
Lutz, Matthias [2 ]
Zugck, Christian [5 ]
Boeger, Rainer H. [1 ]
Frey, Norbert [2 ]
Schwedhelma, Edzard [1 ]
机构
[1] Univ Med Ctr Hamburg Eppendorf, Dept Clin Pharmacol & Toxicol, Hamburg, Germany
[2] Univ Med Ctr Schleswig Holstein, Dept Internal Med Cardiol & Angiol 3, Kiel, Germany
[3] Univ Med Ctr Hamburg Eppendorf, Dept Neurol, Hamburg, Germany
[4] Univ Med Ctr Hamburg Eppendorf, Hamburg, Germany
[5] Univ Med Ctr Heidelberg, Dept Internal Med Cardiol Pulmonol & Angiol 3, Heidelberg, Germany
关键词
Homoarginine; Heart failure; AGAT; NO; Biomarker; CARDIOVASCULAR RISK; NITRIC-OXIDE;
D O I
10.1016/j.ijcard.2013.07.099
中图分类号
R5 [内科学];
学科分类号
100201 [内科学];
摘要
[No abstract available]
引用
收藏
页码:4907 / 4909
页数:3
相关论文
共 10 条
[1]
Atzler D, 2011, CIRCULATION, V124
[2]
Stable isotope dilution assay for liquid chromatography-tandem mass spectrometric determination of L-homoarginine in human plasma [J].
Atzler, Dorothee ;
Mieth, Maren ;
Maas, Renke ;
Boeger, Rainer H. ;
Schwedhelm, Edzard .
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2011, 879 (23) :2294-2298
[3]
Myocardial expression of the arginine: Glycine amidinotransferase gene is elevated in heart failure and normalized after recovery - Potential implications for local creatine synthesis [J].
Cullen, Martin E. ;
Yuen, Ada H. Y. ;
Felkin, Leanne E. ;
Smolenski, Ryszard T. ;
Hall, Jennifer L. ;
Grindle, Suzanne ;
Miller, Leslie W. ;
Birks, Emma J. ;
Yacoub, Magdi H. ;
Barton, Paul J. R. .
CIRCULATION, 2006, 114 :I16-I20
[4]
Promiscuous activity of arginine:glycine amidinotransferase is responsible for the synthesis of the novel cardiovascular risk factor homoarginine [J].
Davids, Mariska ;
Ndika, Joseph D. T. ;
Salomons, Gajja S. ;
Blom, Henk J. ;
Teerlink, Tom .
FEBS LETTERS, 2012, 586 (20) :3653-3657
[5]
Homoarginine, Cardiovascular Risk, and Mortality [J].
Maerz, Winfried ;
Meinitzer, Andreas ;
Drechsler, Christiane ;
Pilz, Stefan ;
Krane, Vera ;
Kleber, Marcus E. ;
Fischer, Joachim ;
Winkelmann, Bernhard R. ;
Boehm, Bernhard O. ;
Ritz, Eberhard ;
Wanner, Christoph .
CIRCULATION, 2010, 122 (10) :967-975
[6]
Nitric oxide and cardiac function - Ten years after, and continuing [J].
Massion, PB ;
Feron, O ;
Dessy, C ;
Balligand, JL .
CIRCULATION RESEARCH, 2003, 93 (05) :388-398
[7]
Substrate specificity of NO synthases:: Detailed comparison of L-arginine, homo-L-arginine, their Nω-hydroxy derivatives, and Nω-hydroxynor-L-arginine [J].
Moali, C ;
Boucher, JL ;
Sari, MA ;
Stuehr, DJ ;
Mansuy, D .
BIOCHEMISTRY, 1998, 37 (29) :10453-10460
[8]
Nitric oxide's role in the heart: control of beating or breathing? [J].
Paulus, WJ ;
Bronzwaer, JGF .
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY, 2004, 287 (01) :H8-H13
[9]
Osteopontin, a New Prognostic Biomarker in Patients With Chronic Heart Failure [J].
Rosenberg, Mark ;
Zugck, Christian ;
Nelles, Manfred ;
Juenger, Claus ;
Frank, Derk ;
Remppis, Andrew ;
Giannitsis, Evangelos ;
Katus, Hligo A. ;
Frey, Norbert .
CIRCULATION-HEART FAILURE, 2008, 1 (01) :43-49
[10]
Cardiomyocytes as effectors of nitric oxide signalling [J].
Seddon, Mike ;
Shah, Ajay M. ;
Casadei, Barbara .
CARDIOVASCULAR RESEARCH, 2007, 75 (02) :315-326