Dehydro-thermally cross-linked collagen-poly(vinyl alcohol) blends: Mechanical, biological and surface properties

被引：6

作者：

Cascone, MG ^{[1
]}

Lazzeri, L ^{[1
]}

Barbani, N ^{[1
]}

Polacco, G ^{[1
]}

Pollicino, A ^{[1
]}

Giusti, P ^{[1
]}

机构：

[1] UNIV CATANIA,FAC ENGN,INST CHEM,I-95125 CATANIA,ITALY

来源：

JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE | 1996年 / 7卷 / 05期

关键词：

D O I：

10.1007/BF00058570

中图分类号：

R318 [生物医学工程];

学科分类号：

0831 ;

摘要：

The mechanical, biological and surface properties of films, based on blends of soluble collagen and poly(vinyl alcohol), were investigated. Films prepared by casting were cross-linked by a dehydro-thermal treatment. The mechanical behaviour of the materials was studied by dynamic-mechanical thermal analysis. The biological properties of the films were evaluated by performing cytotoxicity and cytocompatibility in vitro tests. Surface characterization was carried out by X-ray electron spectroscopy. The results obtained indicate that these materials behave as two-phase systems and a remarkable enrichment of collagen in the surface with respect to the bulk was observed. Cytocompatibility tests show that the blending of the two polymers creates a better substrate for cell growth in comparison with pure components.

引用

页码：297 / 300

页数：4

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