Clinical comparison of the Bactec Mycosis IC/F, BacT/Alert FA, and BacT/Alert FN blood culture vials for the detection of candidemia

被引:40
作者
Ericson, Eva-Lena [1 ]
Klingspor, Lena [1 ]
Ullberg, Mans [1 ]
Ozenci, Volkan [1 ]
机构
[1] Karolinska Inst, Karolinska Univ Hosp, Div Clin Microbiol F 72, SE-14186 Stockholm, Sweden
关键词
Candidemia; Blood culture; Yeast; SYSTEM; MEDIA; TIME; PCR;
D O I
10.1016/j.diagmicrobio.2012.02.020
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
The present study analyzed the performance of Bactec Mycosis IC/F, BacT/Alert FA, and BacT/Alert FN vials in detection and time to detection (TTD) of Candida spp. in 179 simultaneous blood cultures. The Mycosis IC/F, BacT/Alert FA, and BacT/Alert FN vials could detect Candida spp. in 144 (80.45%) of 179, 149 (83.24%) of 179, and 8 (4.47%) of 179 samples, respectively. With the presence of antifungal therapy, the numbers of positive vials were higher in BacT/Alert FA compared to Mycosis IC/F, 87/99 versus 73/99, respectively (P < 0.05). TTD (SD) for C. albicans was shorter in Mycosis IC/F than in BacT/Alert FA vials without antifungal therapy, 20.89 (9.33) versus 28.26 (9.77), respectively (P < 0.01). The detection of Candida spp., with concomitant bacteremia, was higher in Mycosis IC/F than in BacT/Alert FA vials, 28/30 and 19/30, respectively (P = 0.01). The present data show that the use of Bactec Mycosis IC/F together with BacT/Alert FA vials might improve the detection of Candida app. (C) 2012 Elsevier Inc. All rights reserved.
引用
收藏
页码:153 / 156
页数:4
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