Supraphos:: A supramolecular strategy to prepare bidentate ligands

被引：132

作者：

Slagt, VF ^{[1
]}

Röder, M ^{[1
]}

Kamer, PCJ ^{[1
]}

van Leeuwen, PWNM ^{[1
]}

Reek, JNH ^{[1
]}

机构：

[1] Univ Amsterdam, Vant Hoff Inst Mol Sci, NL-1018 WV Amsterdam, Netherlands

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2004年 / 126卷 / 13期

关键词：

D O I：

10.1021/ja038955f

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

We report a new strategy for the preparation of chelating bidentate ligands, which involves just the mixing of two monodentate ligands functionalized with complementary binding sites. In the current example, the assembly process is based on selective metal?ligand interactions, using phosphite zinc(II) porphyrins 1?6 and the nitrogen donor ligands b?i. From only 16 monodentate ligands, a library of 60 palladium catalysts based on 48 bidentate ligand assemblies has been prepared. The relatively small catalyst library gave a large variety in the selectivity of the alkylation of rac-1,3-diphenyl-2-propenyl acetate. Importantly, small variations in the building blocks lead to large differences in the enantioselectivity imposed by the catalyst (up to 97% ee). Copyright © 2004 American Chemical Society.

引用

页码：4056 / 4057

页数：2

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