Enantioselective addition of diethylzinc to benzaldehyde catalyzed by ferrocenic amino-alcohols combining centered and planar chiralities

被引：13

作者：

Malézieux, B

Andrés, R

Gruselle, M

Rager, MN

Thorimbert, S

机构：

[1] Univ Paris 06, CNRS, Unite 7071, Lab Chim Inorgan & Mat Mol, F-75252 Paris 05, France

[2] Ecole Natl Super Chim Paris, Serv RMN, F-75231 Paris, France

[3] Univ Paris 06, UMR 7611, Lab Chim Organ Synth, F-75252 Paris 05, France

来源：

TETRAHEDRON-ASYMMETRY | 1999年 / 10卷 / 17期

关键词：

D O I：

10.1016/S0957-4166(99)00307-9

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

Diastereomeric ferrocenic amino-alcohols combining three elements of chirality (one of which is a ferrocenic plane) are tested as catalysts in the alkylation of benzaldehyde with diethylzinc. Good to excellent yields and ees were obtained and show correlation between the metallocenic chirality and the configuration of the resulting 1-phenyl-1-propanol. (C) 1999 Elsevier Science Ltd. All rights reserved.

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页码：3253 / 3257

页数：5

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