Fluid-structure interaction within realistic three-dimensional models of the aneurysmatic aorta as a guidance to assess the risk of rupture of the aneurysm

被引:267
作者
Di Martino, ES
Guadagni, G
Fumero, A
Ballerini, G
Spirito, R
Biglioli, P
Redaelli, A [1 ]
机构
[1] Politecn Milan, Dept Bioengn, I-20133 Milan, Italy
[2] IRCCS, Ctr Cardiol, Vasc Unit, Milan, Italy
[3] IRCCS, Ctr Cardiol, Dept Radiol, Milan, Italy
关键词
aortic aneurysm; wall mechanics; fluid-structure interaction;
D O I
10.1016/S1350-4533(01)00093-5
中图分类号
R318 [生物医学工程];
学科分类号
0831 ;
摘要
Abdominal aortic aneurysm (AAA) disease is a degenerating process whose ultimate event is the rupture of the vessel wall. Rupture occurs when the stresses acting on the wall rise above the strength of the AAA wall tissue. The complex mechanical interaction between blood flow and wall dynamics in a three dimensional custom model of a patient AAA was studied by means of computational coupled fluid-structure interaction analysis. Real 3D AAA geometry is obtained from CT scans image processing. The results provide a quantitative local evaluation of the stresses due to local structural and fluid dynamic conditions. The method accounts for the complex geometry of the aneurysm, the presence of a thrombus and the interaction between solid and fluid. A proven clinical efficacy may promote the method as a tool to determine factual aneurysm risk of rupture and aid the surgeon to refer elective surgery patients. (C) 2002 Published by Elsevier Science Ltd on behalf of IPEM.
引用
收藏
页码:647 / 655
页数:9
相关论文
共 42 条
[1]  
BALLARD DJ, 1998, EUR J VASC ENDOVASC, V16, P104
[2]   Steady flow in an aneurysm model: Correlation between fluid dynamics and blood platelet deposition [J].
Bluestein, D ;
Niu, L ;
Schoephoerster, RT ;
Dewanjee, MK .
JOURNAL OF BIOMECHANICAL ENGINEERING-TRANSACTIONS OF THE ASME, 1996, 118 (03) :280-286
[3]   Risk factors associated with rapid growth of small abdominal aortic aneurysms [J].
Chang, JB ;
Stein, TA ;
Liu, JP ;
Dunn, ME .
SURGERY, 1997, 121 (02) :117-122
[4]   VARIABLES THAT AFFECT THE EXPANSION RATE AND OUTCOME OF SMALL ABDOMINAL AORTIC-ANEURYSMS [J].
CRONENWETT, JL ;
SARGENT, SK ;
WALL, MH ;
HAWKES, ML ;
FREEMAN, DH ;
DAIN, BJ ;
CURE, JK ;
WALSH, DB ;
ZWOLAK, RM ;
MCDANIEL, MD ;
SCHNEIDER, JR .
JOURNAL OF VASCULAR SURGERY, 1990, 11 (02) :260-269
[5]  
DARLING RC, 1977, CIRCULATION, V56, P161
[6]   Biomechanics of abdominal aortic aneurysm in the presence of endoluminal thrombus: Experimental characterisation and structural static computational analysis [J].
Di Martino, E ;
Mantero, S ;
Inzoli, F ;
Melissano, G ;
Astore, D ;
Chiesa, R ;
Fumero, R .
EUROPEAN JOURNAL OF VASCULAR AND ENDOVASCULAR SURGERY, 1998, 15 (04) :290-299
[7]  
Di MArtino E, 2001, COMPUTER METHODS IN BIOMECHANICS AND BIOMEDICAL ENGINEERING - 3, P719
[8]  
DIMARTINO E, 1999, THESIS U STUDI MILAN
[9]  
DOBRIN PB, 1984, ARCH SURG-CHICAGO, V119, P405
[10]   The influence of shape on the stresses in model abdominal aortic aneurysms [J].
Elger, DF ;
Blackketter, DM ;
Budwig, RS ;
Johansen, KH .
JOURNAL OF BIOMECHANICAL ENGINEERING-TRANSACTIONS OF THE ASME, 1996, 118 (03) :326-332