Transformation of Tetracyclines Mediated by Mn(II) and Cu(II) Ions in the Presence of Oxygen

被引：155

作者：

Chen, Wan-Ru ^{[1
]}

Huang, Ching-Hua ^{[1
]}

机构：

[1] Georgia Inst Technol, Sch Civil & Environm Engn, Atlanta, GA 30332 USA

来源：

ENVIRONMENTAL SCIENCE & TECHNOLOGY | 2009年 / 43卷 / 02期

基金：

美国国家科学基金会;

关键词：

SOLID-PHASE EXTRACTION; BIOLOGICAL-FLUIDS; LIQUID-CHROMATOGRAPHY; OXYTETRACYCLINE; CHLORTETRACYCLINE; DEGRADATION; MANGANESE; SORPTION; BINDING; ANHYDROTETRACYCLINE;

D O I：

10.1021/es802295r

中图分类号：

X [环境科学、安全科学];

学科分类号：

08 ; 0830 ;

摘要：

Complexation of tetracyclines (TCs) with dissolved Mn-II and Cull ions were found to significantly enhance the transformation of these antibiotics in the presence of oxygen at pH 8-9.5 and pH 4-6, respectively. In the TC-Mn-II-O-2 system, oxidation of the TC-complexed Mn-II to Mn-III by oxygen occurs, followed by oxidation of TC by Mn-III to regenerate Mn-II. In the TC-CU"-02 system, Cu-II oxidizes TC within the complex and the yielded Cu-I is reoxidized by the present oxygen. Opposite reactivity trends were observed with the two metals: OTC (oxytetracycline) > TTC (tetracycline) >> iso-CTC (isochlorotetracycline) for the Mn-II-mediated reaction, whereas CTC > TTC > OTC > epimers for the Cu-II-mediated reaction. The reactivity results and examination of TC-metal ion complexation and transformation products suggest that the BCD-ring and A-ring of TC are crucial to interactwith Mn-II and Cu-II, respectively. This study highlights that the fate of TCs in aquatic environments may differ significantly by their strong interactions with different metal species present in the systems.

引用

页码：401 / 407

页数：7

共 44 条

[1] MECHANISM OF DISPROPORTIONATION OF SUPEROXIDE RADICALS [J].

BIELSKI, BHJ ;

ALLEN, AO .

JOURNAL OF PHYSICAL CHEMISTRY, 1977, 81 (11) :1048-1050

[2] On the mechanism of TiO2-photocatalyzed degradation of aniline derivatives [J].

Canle, M ;

Santaballa, JA ;

Vulliet, E .

JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY, 2005, 175 (2-3) :192-200

[3] DIRECT PROPORTIONALITY OF URINARY EXCRETION RATE AND SERUM LEVEL OF TETRACYCLINE IN HUMAN SUBJECTS [J].

CHULSKI, T ;

JOHNSON, RH ;

WAGNER, JG ;

SCHLAGEL, CA .

NATURE, 1963, 198 (487) :450-&

[4] CHEMISTRY OF TETRACYCLINES [J].

CLIVE, DLJ .

QUARTERLY REVIEWS, 1968, 22 (04) :435-&

[5] TiO2-photocatalyzed As(III) oxidation in aqueous suspensions:: Reaction kinetics and effects of adsorption [J].

Ferguson, MA ;

Hoffmann, MR ;

Hering, JG .

ENVIRONMENTAL SCIENCE & TECHNOLOGY, 2005, 39 (06) :1880-1886

[6] Sorption of oxytetracycline to iron oxides and iron oxide-rich soils [J].

Figueroa, RA ;

Mackay, AA .

ENVIRONMENTAL SCIENCE & TECHNOLOGY, 2005, 39 (17) :6664-6671

[7]

Gianessi LP., 1995, Pesticide use in US crop production

[8] Chemicals and biological products used in south-east Asian shrimp farming, and their potential impact on the environment -: a review [J].

Gräslund, S ;

Bengtsson, BE .

SCIENCE OF THE TOTAL ENVIRONMENT, 2001, 280 (1-3) :93-131

[9] Interaction of tetracycline with aluminum and iron hydrous oxides [J].

Gu, C ;

Karthikeyan, KG .

ENVIRONMENTAL SCIENCE & TECHNOLOGY, 2005, 39 (08) :2660-2667

[10] Characterisation of the abiotic degradation pathways of oxytetracyclines in soil interstitial water using LC-MS-MS [J].

Halling-Sorensen, B ;

Lykkeberg, A ;

Ingerslev, F ;

Blackwell, P ;

Tjornelund, J .

CHEMOSPHERE, 2003, 50 (10) :1331-1342

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