Genomics applications to biotech traits: a revolution in progress?

被引:31
作者
Gutterson, N [1 ]
Zhang, JZ [1 ]
机构
[1] Mendel Biotechnol, Hayward, CA 94545 USA
关键词
D O I
10.1016/j.pbi.2003.12.002
中图分类号
Q94 [植物学];
学科分类号
071001 ;
摘要
Twenty years since the inception of the agricultural biotechnology era, only two products have had a significant impact in the market place: herbicide-resistant and insect-resistant crops. Additional products have been pursued but little success has been achieved, principally because of limited understanding of key genetic intervention points. Genomics tools have fueled a new strategy for identifying candidate genes. Primarily thanks to the application of functional genomics in Arabidopsis and other plants, the industry is now overwhelmed with candidate genes for transgenic intervention points. This success necessitates the application of genomics to the rapid validation of gene function and mode of action. As one example, the development of C-box binding factors (CBFs) for enhanced freezing and drought tolerance has been rapidly advanced because of the improved understanding generated by genomics technologies.
引用
收藏
页码:226 / 230
页数:5
相关论文
共 49 条
[1]   Arabidopsis AtMYC2 (bHLH) and AtMYB2 (MYB) function as transcriptional activators in abscisic acid signaling [J].
Abe, H ;
Urao, T ;
Ito, T ;
Seki, M ;
Shinozaki, K ;
Yamaguchi-Shinozaki, K .
PLANT CELL, 2003, 15 (01) :63-78
[2]   Identification of the SAAT gene involved in strawberry flavor biogenesis by use of DNA microarrays [J].
Aharoni, A ;
Keizer, LCP ;
Bouwmeester, HJ ;
Sun, ZK ;
Alvarez-Huerta, M ;
Verhoeven, HA ;
Blaas, J ;
van Houwelingen, AMML ;
De Vos, RCH ;
van der Voet, H ;
Jansen, RC ;
Guis, M ;
Mol, J ;
Davis, RW ;
Schena, M ;
van Tunen, AJ ;
O'Connell, AP .
PLANT CELL, 2000, 12 (05) :647-661
[3]   Genome-wide Insertional mutagenesis of Arabidopsis thaliana [J].
Alonso, JM ;
Stepanova, AN ;
Leisse, TJ ;
Kim, CJ ;
Chen, HM ;
Shinn, P ;
Stevenson, DK ;
Zimmerman, J ;
Barajas, P ;
Cheuk, R ;
Gadrinab, C ;
Heller, C ;
Jeske, A ;
Koesema, E ;
Meyers, CC ;
Parker, H ;
Prednis, L ;
Ansari, Y ;
Choy, N ;
Deen, H ;
Geralt, M ;
Hazari, N ;
Hom, E ;
Karnes, M ;
Mulholland, C ;
Ndubaku, R ;
Schmidt, I ;
Guzman, P ;
Aguilar-Henonin, L ;
Schmid, M ;
Weigel, D ;
Carter, DE ;
Marchand, T ;
Risseeuw, E ;
Brogden, D ;
Zeko, A ;
Crosby, WL ;
Berry, CC ;
Ecker, JR .
SCIENCE, 2003, 301 (5633) :653-657
[4]   Salt tolerance conferred by overexpression of a vacuolar Na+/H+ antiport in Arabidopsis [J].
Apse, MP ;
Aharon, GS ;
Snedden, WA ;
Blumwald, E .
SCIENCE, 1999, 285 (5431) :1256-1258
[5]   Three genes that affect sugar sensing (Abscisic Acid Insensitive 4, Abscisic Acid Insensitive 5, and Constitutive Triple Response 1) are differentially regulated by glucose in arabidopsis [J].
Arroyo, A ;
Bossi, F ;
Finkelstein, RR ;
León, P .
PLANT PHYSIOLOGY, 2003, 133 (01) :231-242
[6]   Cell numbers and leaf development in Arabidopsis:: a functional analysis of the STRUWWELPETER gene [J].
Autran, D ;
Jonak, C ;
Belcram, K ;
Beemster, GTS ;
Kronenberger, J ;
Grandjean, O ;
Inzé, D ;
Traas, J .
EMBO JOURNAL, 2002, 21 (22) :6036-6049
[7]   Redundancy based detection of sequence polymorphisms in expressed sequence tag data using autoSNP [J].
Barker, G ;
Batley, J ;
O'Sullivan, H ;
Edwards, KJ ;
Edwards, D .
BIOINFORMATICS, 2003, 19 (03) :421-422
[8]   Mining for single nucleotide polymorphisms and insertions/deletions in maize expressed sequence tag data [J].
Batley, J ;
Barker, G ;
O'Sullivan, H ;
Edwards, KJ ;
Edwards, D .
PLANT PHYSIOLOGY, 2003, 132 (01) :84-91
[9]   Cell cycle:: the key to plant growth control? [J].
Beemster, GTS ;
Fiorani, F ;
Inzé, D .
TRENDS IN PLANT SCIENCE, 2003, 8 (04) :154-158
[10]   Constitutive expression of ETHYLENE-RESPONSE-FACTOR1 in Arabidopsis confers resistance to several necrotrophic fungi [J].
Berrocal-Lobo, M ;
Molina, A ;
Solano, R .
PLANT JOURNAL, 2002, 29 (01) :23-32